Christina Applegate and Will Arnett in NBC's 'Up All Night': Watch the full series trailer
They play a couple who's been married for seven years and have just had their first child, which they quickly discover puts a major dent in their previous, not-quite-grown-up lifestyle. Maya Rudolph also stars.
Applegate, who's doing her first series since "Samantha Who?," is a new mom herself, having given birth to daughter Sadie in late January. Arnett also has two young children, so we're guessing they can relate to their roles pretty well.
The series will air at 8 p.m. ET Wednesdays in the fall. The show's trailer is below; more clips are here and here.