After being raped at 14, Jacqui found solace in food, and as an adult weighed 355 pounds.
Tony drinks about 2,000 calories a day in juice alone and topped out at 398 pounds.
Chris Powell, who transforms the super-obese, helps both in the second season of ABC's "Extreme Makeover: Weight Loss Edition," beginning Sunday, June 3.
Indefatigably upbeat, Powell explains he coaches people if they are in the right place mentally.
"Sometimes people hit rock bottom, and they are open and coachable," Powell tells Zap2it. "Sometimes we just come across someone who says, 'I am struggling, and I just don't like my life the way it is.' "
To make this work, people must be authentic, let down their guard and be ready to accept major changes. In the show, participants meet with physicians and nutritionists. Powell puts them on exercise and diet regimens.
When they start, people are at their largest, in exercise shorts, with men shirtless and women in sports bras. Powell says he never recoils from the sight of that much skin.
"Other people see pictures and go, 'Oh, gross! I can't even look.' But to me, it is fascinating how the body has completely transformed itself," Powell says.
He refers to how, among other physiological changes, legs bow out to sustain the weight. Powell's mission, however, is to transform the body again, this time to a healthy weight and see how the once super-obese, those with BMIs over 50, can once again live healthier, happier lives.
Powell's top tips for losing weight are:
Confess. You need not confide in someone. Look in the mirror and state the problem. "It has nothing to do with weight loss and everything to do with what is happening in your heart," Powell says.
Reassess. What was the commitment? If you're a working mom, exercising three hours a day is likely unattainable. Set reasonable goals.
Recommit. Humans fail. The most important step is starting again.
Photo/Video credit: ABC