Celebrity Spiltsville: Which Hollywood same sex couples will last?

October has been serious Gay Couple Split month. And it could get worse.

Rosie O'Donnell discussed her increasingly rocky relationship with Kelli Carpenter with USA Today.

"Kelli and I love each other very much and we are working on our issues."

Award-winning actress Cherry Jones split from younger girlfriend/actress Sarah Paulson, whom she had been romantically involved with since 2005.She told Us Weekly, "We're not together anymore but we're still the dearest of friends."

And "Grey's Anatomy" alum T.R. Knight split from his adorable boytoy, Mark Cornelsen. Your guess why is probably as good as ours.

Will this gay breakup virus spread through Hollywood? Who will come down with the same sex relationship version of swine flu next?

We've lined up some likely suspects.

--Elizabeth Snead