Look back: 25 great 'Oprah' moments

(Hermann J. Knippertz / Associated Press)
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Pregnant man Thomas Beatie (2008)

In 2008, Oprah introduced the world to the first pregnant man. In his TV interview, Thomas Beatie, right, revealed he used to be a woman. Despite going through sexual reassignment (he's legally considered a man), he was able to keep his ovaries and uterus intact. The married father, who now has three little ones, chose to carry the babies because his wife Nancy, left, is unable to have children.