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The powers: Rage-induced super-strength and invulnerability
The actor: Bill Bixby/Lou Ferrigno
The run: 1978-1982
The villains: Drug lords, corrupt cops, duplicitous family members, and others who prey on the helpless.
The tone: They were going for poignant, but it's hard to take things too seriously when you've got Lou Ferrigno painted green and flexing.
Of note: Don't make him angry. You wouldn't like him when he's angry.