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Jacqui (Jeryl Prescott)
Death episode: "TS-19"
How it happened: She stays behind at the Center for Disease Control with Dr. Jenner (Noah Emmerich) after he initiates a self-destruct sequence. They both die in the explosion after letting the rest of the group escape.
Shock factor: As the last significant death of Season 1, Jacqui's death was notable because she was the first major character to choose to die instead of fighting to survive in the harsh new world.