Veteran series leads Julianna Margulies and Sara Rue have signed on to topline drama pilots at FOX.

According to the industry trades, Margulies will star in "Canterbury's Law," a legal drama about a woman named Elizabeth Canterbury (hence the title, we suspect). Margulies would play the main character, an edgy defense attorney, in the Mike Figgis-directed pilot. She would also get a producer credit.

This will be the first pilot for the Emmy-winning "Snakes on a Plane" star since a little NBC drama called "E.R." Her recent credits include the Sci Fi miniseries "The Lost Room" and a recurring role on HBO's "The Sopranos."

Also at FOX, Rue will play one of the titular medical professionals in the comedic drama "Nurses," playing a married woman who still frequents online dating sites.

Rue starred for four seasons on ABC's comedy "Less That Perfect." She also co-starred on The WB's "Popular" for its two-season run.

In other casting news, Jamie Murray of AMC/BBC's "Hustle," will play a neurologist/demon enthusiast in CBS' drama "Demons," set to star Ron Eldard and Harold Perrineau.