| 7:00 | 7:30 | 8:00 | 8:30 | 9:00 | 9:30 | |
| Sun | In Harm's Way (starts at 6:30 p.m.) | Surviving Suburbia | Valentine, Inc. | Easy Money | ||
| Mon | Gossip Girl | One Tree Hill | ||||
| Tue | 90210 | Privileged | ||||
| Wed | America's Next Top Model | 90210 encore/Stylista (starting Oct. 22) | ||||
| Thu | Smallville | Supernatural | ||||
| Fri | Everybody Hates Chris | The Game | America's Next Top Model (encore presentation) | |||
| Sat | Local programming | |||||
| Legend: | New Show | New Timeslot | Returning Show |